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Can I be able to virtual host an application on a url prefix

I want to run a pyramid cms(Kotti) on top of my website. e.g www.example.com/cms/ will be the root of the cms. Is this possible? How can I do it?

Yes, it's possible. You can use the werkzeug DispatcherMiddleware in your wsgi file to combine your apps. The docs are here

I'm not using flask. My apps are pyramid.

I was pointing you at the middleware. It doesn't care what your apps are implemented in, as long as they are WSGI compliant.

Ok. Thanks very much