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Is it possible?

Here's a typical situation:

I'm working on some data science stuff that will take a couple of days to complete once it gets launched, in a Jupyter notebook. I've been experimenting for a bit but I'm not ready to build a separate script for it just to run it on PythonAnywhere - I want to start it running in PythonAnywhere and then close my laptop and come back to it later.

Is this possible?

Sure, that will normally work fine. There's a chance that the server might have to be rebooted while the script is running, but reboots of notebook servers are pretty rare -- order of once a month or so.